 | Peripheral Receptor Targets for Analgesia: Novel Approaches to Pain Management While considerable advances have been made on pharmacotherapies for many chronic disease states, options available to treat chronic pain have remained relatively unchanged for decades. However, utilizing the receptors involved in peripheral pain transduction mechanisms offers a significant opportunity to create novel therapies for pain. A comprehensive review of peripheral pain mechanisms, Peripheral Receptor Targets for Analgesia: Novel Approaches to Pain Management provides a unique resource that brings together a body of knowledge that was previously widely dispersed. As such, it gives readers a framework for further basic and clinical studies on potential receptor targets, as well as the development of improved topical analgesics. Coverage includes: The latest discoveries by leading researchers relating to the function of various ion channels and receptors in the peripheral nervous system Novel delivery techniques An appendix listing currently available topical analgesic medications A Foreword by Professor Lars Arendt-Nielsen of the Center for Sensory-Motor Interaction (SMI) at Aalborg University An unmatched resource for improving drug therapies and making pain management more efficient, Peripheral Receptor Targets for Analgesia supplies pharmaceutical scientists, pharmacologists, neuroscientists, and graduate and upper-level undergraduate students with a comprehensive, up-to-date reference. Brian Cairns is Canada Research Chair in Neuropharmacology and an Associate Professor in the Faculty of Pharmaceutical Sciences at the University of British Columbia. The author of book chapters (including in Wiley's Handbook of Pharmaceutical Biotechnology ) and more than fifty journal articles, Dr. Cairns also teaches undergraduate and graduate students about pain research and treatment, and contributes to the activities of several well-known pain research societies. |
