Human Polyomaviruses: Molecular and Clinical Perspectives
ISBN: 9780471221944
Platform/Publisher: WOL / Wiley-Liss
Digital rights: Users: Unlimited; Printing: Unlimited; Download: Unlimited
Subjects: Medicine; Basic Medical Sciences;

Our understanding of human polyomaviruses has evolved profoundly in the last fifteen years, creating an urgent need for an updated resource. Drs. Khalili and Stoner have collected the contributions of renowned researchers and clinicians in this cutting-edge volume.

Human Polyomaviruses: Molecular and Clinical Perspectives presents in-depth analyses, comprehensive reviews, and timely assessments of recent discoveries and ongoing controversies focused on these important viral pathogens. Beginning with an historical perspective, this book covers up-to-date investigations into the molecular biology and pathogenesis of human polyomaviruses. All aspects of these persistent infections are subsequently covered, including clinical issues, from diagnosis to information on treatment and drug trials. Central topics are:

BK virus JC virus Simian virus 40 (SV40) and its potential as a human pathogen Progressive multifocal leukoencephalopathy (PML)

This reference is a superb indoctrination for graduate students, medical students, high-level undergraduates, and anyone engaged in the study of DNA viruses and their molecular biology, evolution, transmission, and pathological potential.


Kamel Khalili , PhD, Professor and Chair, Department of Neuroscience, Temple University, is among the leading scientists in the field of human DNA and RNA viruses. Dr Khalili has more than 25 years' experience in studying oncogenic viruses.

Dr. Gerald L Stoner received his Ph.D. in Biochemistry from the College of Physicians and Surgeons of Columbia University in 1974. He did postdoctoral work with Prof. Barry R. Bloom on the immunopathology of demyelination in the Department of Microbiology and Immunology of the Albert Einstein College of Medicine of Yeshiva University. In 1976 he moved to Addis Ababa, Ethiopia where he was a Senior Staff Scientist in the Armauer Hansen Research Institute studying the immunology of leprosy. In 1981 he joined the Laboratory of Experimental Neuropathology in the National Institute of Neurological Disorders and Stroke (NINDS) of the National Institutes of Health with Dr. Henry deF. Webster where he studied the structure of myelin basic protein and began his current work in the neuropathology, molecular virology, and molecular epidemiology of the polyomaviruses in human disease. Since 1988 he has been chief of the Neurotoxicology Section, NINDS.

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