Engineering the Genetic Code - Expanding the Amino Acid Repertoire for the Design of Novel Proteins
ISBN: 9783527607181
Platform/Publisher: WOL / Wiley-VCH
Digital rights: Users: Unlimited; Printing: Unlimited; Download: Unlimited
Subjects: Chemistry; Biochemistry;

The ability to introduce non-canonical amino acids in vivo has greatly expanded the repertoire of accessible proteins for basic research and biotechnological application.
Here, the different methods and strategies to incorporate new or modified amino acids are explained in detail, including a lot of practical advice for first-time users of this powerful technique.
Novel applications in protein biochemistry, genomics, biotechnology and biomedicine made possible by the expansion of the genetic code are discussed and numerous examples are given.
Essential reading for all molecular life scientists who want to stay ahead in their research.

Nediljko Budisa is a group leader at the Max-Planck-Institute of Biochemistry in Martinsried near Munich (Germany). He studied Chemistry and Biology at the University of Zagreb (Croatia) before joining the group of Nobel Prize Winner Robert Huber at Martinsried to obtain his PhD degree. During postdoctoral work with R. Huber and L. Moroder he led an independent research team in protein engineering. In 2004, Dr. Budisa received the BioFuture Award of the German Federal Ministry for Research and Education.

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