The Pathogenic Spirochetes: strategies for evasion of host immunity and persistence
ISBN: 9781461454045
Platform/Publisher: SpringerLink / Springer US
Digital rights: Users: unlimited; Printing: unlimited; Download: unlimited
Subjects: Biomedical and Life Sciences;

​This book explores the many mechanisms by which the most prevalent Spirochetal pathogens persist in a healthy immune-competent host. Among them are the direct and indirect suppression of host immune signals, phase and antigenic variation, escaping recognition by host complement proteins, and seclusion into immune privileged sites. We also explore antibiotic therapy for control of infection, a baffling topic that lends itself to exalted interpretation.

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