Autologous Stem Cell Transplantation: Biological and Clinical Results in Malignancies
ISBN: 9781003077343
Platform/Publisher: Taylor & Francis / Routledge
Digital rights: Users: Unlimited; Printing: Unlimited; Download: Unlimited
Subjects: Bioscience; Pharmaceutical Science; Pharmaceutical Technology;

This textbook integrates basic research and clinical aspects underlying the most recent results in those malignant diseases where progress is most effective.
Recent evidence shows that higher doses are better in inducing higher cure rates in hematological neoplasias, although myeloblation related to dose intensity can be a limiting factor. The toxicity can now be controlled with autologous marrow and peripheral blood progenitor cell transplantation, used with or without growth factors. The combination of high dose chemoradiotherapy followed by re-infusion of autologous stem cells constitute a dramatic advance in the treatment of refactory and relapse hematological neoplasias.

Angelo Carella is the Coordinator of the Hematology and ABMT Section at Ospedale S. Martino, Genoa, Italy. A prolific contributor to the literature on hematology, particularly in the leukemias and lymphomas, his publications include six requested chapters in books and over 200 research and clinical articles.

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